Understanding Cortisone Injections: What to Expect Before, During, and After

When pain becomes persistent—whether from arthritis, tendinitis, or a spinal issue—cortisone injections are often recommended as a quick and effective treatment. But many patients aren’t sure what cortisone is, how long it lasts, or what the experience is actually like.

At Ospina Medical in New York City, Dr. Matthew Kohler specializes in using image-guided cortisone injections  to provide relief in the most precise, minimally invasive way possible. Here's what you should know before scheduling a cortisone shot.

What Is a Cortisone Injection?

Cortisone is a powerful anti-inflammatory medication. When injected directly into an area of inflammation—like a joint, tendon sheath, or around a spinal nerve—it helps calm swelling, reduce pain, and improve movement.

These injections are commonly used to treat:

Knee, hip, or shoulder arthritis

Tendinitis or bursitis (e.g., rotator cuff, tennis elbow)

Carpal tunnel syndrome

Sciatica or spinal stenosis

Other localized joint and soft tissue pain

What to Expect Before the Injection

Dr. Kohler will begin with a full evaluation, reviewing your medical history and any imaging (X-rays or MRIs). If a cortisone injection is appropriate, he’ll explain the procedure in detail and answer any questions.

There’s no major prep required, but let your doctor know if you’re on blood thinners, have diabetes, or have had issues with steroids in the past.

What Happens During the Procedure?

The area is cleaned and numbed with a local anesthetic

Using ultrasound or fluoroscopy guidance, Dr. Kohler inserts a small needle into the exact area of inflammation

Cortisone, often combined with a numbing agent, is injected directly into the target site

The entire procedure typically takes less than 15 minutes. Most patients report only mild discomfort during the injection.

What to Expect Afterward

Pain Relief: You may feel relief within a few hours if a numbing medication was used, but true cortisone effects begin within 2–5 days.

Duration: Relief can last from several weeks to several months, depending on your condition and activity level.

Post-Injection Care: You may be advised to rest the area for 24–48 hours and avoid strenuous activity temporarily.

Some people experience a mild “flare” of pain for a day or two after the injection—this is normal and usually short-lived.

Are Cortisone Injections Safe?

Yes, when performed by a trained specialist. However, they are not a long-term solution and should be used strategically—not repeatedly.

At Ospina Medical, Dr. Kohler typically limits cortisone use to 3–4 injections per year in the same joint to avoid side effects like tissue thinning or joint degradation.

Is Cortisone Right for You?

Cortisone injections can be a powerful tool in a comprehensive treatment plan. For some, they provide enough relief to start physical therapy. For others, they serve as a bridge while exploring regenerative treatments like PRP or stem cells.

If you're dealing with persistent joint or back pain, schedule a consultation at Ospina Medical to find out if a cortisone injection is right for you—and how it fits into your overall recovery strategy.